Description

Ethyl 4-Hydroxy-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic cores. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of target drug molecules, especially kinase inhibitors and other small-molecule therapeutics.
• Drug Discovery & Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries and exploring structure-activity relationships (SAR) in early-stage R&D.
• Process Chemistry & Scale-Up: Used in the development and optimization of robust, scalable synthetic routes for candidate drugs.
• Chemical Reference Standard: Employed as an analytical standard for quality control, method development, and regulatory submissions.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental research and custom synthesis projects.

Basic Information

Product Name	Ethyl 4-Hydroxy-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine-5-Carboxylate
CAS No.	1388893-76-2
Molecular Formula	C12H12N2O3S
Molecular Weight	264.30 g/mol
Synonyms	Ethyl 4-hydroxy-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine-5-carboxylate; 5H-Cyclopenta[4,5]thieno[2,3-d]pyrimidine-5-carboxylic acid, 4-hydroxy-6,7-dihydro-, ethyl ester; 1388893-76-2; Cyclopentathienopyrimidine derivative; 4-Hydroxy-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxy-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.