Description

7-Bromo-6-Chloro-1H-Indole-2-Carboxylic Acid is a high-purity, halogenated indole derivative serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a versatile building block for the synthesis of complex bioactive molecules, particularly in medicinal chemistry. This compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, where it is used to create novel drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for small molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop compounds with improved efficacy and selectivity.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, or plant growth regulators that utilize the indole scaffold.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds due to its reactive carboxylic acid and halogen substituents.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or tagged molecules for biochemical and diagnostic applications.

Basic Information

Product Name	7-Bromo-6-Chloro-1H-Indole-2-Carboxylic Acid
CAS No.	1388069-91-7
Molecular Formula	C9H5BrClNO2
Molecular Weight	274.50 g/mol
Synonyms	7-Bromo-6-chloro-1H-indole-2-carboxylic acid; 2-Carboxy-7-bromo-6-chloroindole; 6-Chloro-7-bromoindole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, 7-bromo-6-chloro-; 7-Bromo-6-chloroindole-2-carboxylic acid; 1388069-91-7; 7-Br-6-Cl-1H-indole-2-COOH
EINECS	Contact for details

Quality Control

Our 7-Bromo-6-Chloro-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by IR, NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.