Description

5-Chloro-2-Iodoindole is a halogenated indole derivative, a versatile and high-value building block in advanced organic synthesis. This compound is prized for its unique reactivity profile, enabling the construction of complex heterocyclic frameworks. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and receptor modulator research.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for functional organic materials, including organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology: Employed as a probe or labeling agent in biochemical studies due to the reactivity of the iodine moiety.
• Cross-Coupling Reactions: Acts as a pivotal substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	5-Chloro-2-Iodoindole
CAS No.	1388032-50-5
Molecular Formula	C8H5ClIN
Molecular Weight	277.49 g/mol
Synonyms	2-Iodo-5-chloro-1H-indole; 5-Chloro-1H-2-iodoindole; 5-Chloro-2-iodo-1H-indole; 1H-Indole, 5-chloro-2-iodo-; 5-Chloro-2-iodindol; 5-Chloro-2-iodoindole
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2-Iodoindole is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.