Description

n-Acetyl-L-Aspartic Acid-D3 is a stable isotope-labeled analog of the endogenous metabolite N-acetyl-L-aspartic acid (NAA). This high-purity deuterated compound is essential for advanced analytical research, providing a critical internal standard for precise quantification. It is primarily utilized by researchers and manufacturers in the fields of metabolomics, neuroscience, and pharmaceutical development who require accurate mass spectrometry and NMR analysis.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference in LC-MS and GC-MS analysis of biological samples for NAA and related metabolites.
• Metabolomics Research: Enables accurate tracking and quantification of NAA pathways in studies of cellular metabolism and disease states.
• Neuroscience & Biomarker Discovery: Critical for investigating the role of NAA in neurological function and as a potential biomarker for conditions like Canavan disease and brain tumors.
• Pharmaceutical Development: Supports drug metabolism and pharmacokinetics (DMPK) studies for compounds affecting the aspartate pathway.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Serves as a deuterated tracer for metabolic flux analysis and structural studies.
• Quality Control & Reference Material: Acts as a certified reference material (CRM) for ensuring accuracy in diagnostic assays and analytical method validation.

Basic Information

Item	Details
Product Name	n-Acetyl-L-Aspartic Acid-D3
CAS No.	1383929-94-9
Molecular Formula	C6H6D3NO5
Molecular Weight	177.14 g/mol
Synonyms	N-Acetyl-L-aspartic-2,3,3-d3 Acid; (2S)-2-Acetamido-3,3-dideutero-4-deuteriooxy-4-oxobutanoic Acid; N-Acetyl-L-aspartic Acid-d3; NAA-d3; Deuterated N-Acetyl-L-aspartic Acid; N-Acetyl-DL-aspartic-2,3,3-d3 Acid (mixture); Ac-Asp-OH-d3; L-N-Acetylaspartic Acid-d3
EINECS	Contact for details

Quality Control

Our n-Acetyl-L-Aspartic Acid-D3 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for assay, isotopic enrichment (D-content), and impurity profiles via HPLC, NMR, and MS. We adhere to ISO 9001 guidelines, and specifications can be tailored to meet specific research or cGMP requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.