Description

Pristanic Acid-D3 is a stable isotope-labeled analog of pristanic acid, a key branched-chain fatty acid biomarker. This deuterated compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring analytical accuracy and reproducibility. It is primarily required by research laboratories and diagnostic manufacturers in the fields of clinical biochemistry, metabolic disorder research, and newborn screening for peroxisomal disorders.

Application

• Internal Standard for Mass Spectrometry (LC-MS/MS, GC-MS): Enables precise quantification of endogenous pristanic acid in complex biological matrices like plasma, serum, and dried blood spots.
• Clinical Diagnostics and Newborn Screening: Critical for developing and running assays to diagnose Refsum disease and other peroxisomal biogenesis disorders (e.g., Zellweger spectrum).
• Biomarker Research: Used in studies investigating fatty acid α-oxidation pathways, lipid metabolism, and the biochemical basis of related diseases.
• Method Development and Validation: Serves as a reference material for establishing and validating analytical methods in accordance with CLIA, ISO 15189, or other regulatory guidelines.
• Quality Control in Diagnostic Kits: Incorporated into commercial diagnostic kits and reagents to ensure lot-to-lot consistency and reliable patient results.
• Pharmacokinetic and Metabolic Studies: Utilized in research to track the metabolism and distribution of branched-chain fatty acids and related therapeutics.

Basic Information

Product Name	Pristanic Acid-D3
CAS No.	1383920-14-6
Molecular Formula	C20H37D3O2
Molecular Weight	315.53 g/mol (approx.)
Synonyms	2,6,10,14-Tetramethylpentadecanoic-d3 Acid; Deuterated Pristanic Acid; Pristanic Acid (trimethyl-D3); 2,6,10,14-Tetramethylpentadecanoic-16,16,16-d3 Acid; Pristanic Acid-d3 Internal Standard; Isotope Labeled Pristanic Acid; (R,S)-Pristanic Acid-d3; 16,16,16-D3-Pristanic Acid
EINECS	Contact for details

Quality Control

Our Pristanic Acid-D3 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic enrichment and chemical purity. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic purity, and solvent residues is provided to ensure compliance with research and diagnostic industry standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. The product is stable under these conditions for at least 24 months from the date of receipt.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Chemical Purity)
Isotopic Purity (MS)	≥ 98 atom % D
Isotopic Enrichment	≥ 99% D3
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.