Description

Dimethyl 3-(Aminomethyl)Benzylphosphonate Oxalate is a high-purity, specialty organophosphorus compound with a bifunctional structure, serving as a critical building block in advanced chemical synthesis. Its unique combination of an aminomethyl group and a phosphonate ester, stabilized as an oxalate salt, makes it a versatile intermediate for introducing specific molecular motifs. This product is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical sectors who require precise, scalable, and reliable synthetic intermediates for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders or requiring phosphonate-based bioisosteres.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, insecticides, and plant growth regulators that incorporate phosphonate functionalities.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphonate-containing ligands used in asymmetric catalysis and metal complexation.
• Peptide Mimetics and Prodrug Design: The aminomethyl phosphonate moiety is valuable for constructing phosphate prodrugs and non-hydrolyzable peptide analogs in medicinal chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers, metal-organic frameworks (MOFs), or surface modifiers where precise chemical grafting is required.
• Chemical Biology Probes: Useful for creating activity-based probes or affinity labels to study enzyme mechanisms, particularly those involving phosphate transfer.

Basic Information

Product Name	Dimethyl 3-(Aminomethyl)Benzylphosphonate Oxalate
CAS No.	1383133-17-2
Molecular Formula	C12H18NO7P
Molecular Weight	319.25 g/mol
Synonyms	Dimethyl (3-(aminomethyl)phenyl)methylphosphonate oxalate; 3-(Aminomethyl)benzylphosphonic Acid Dimethyl Ester Oxalate; (3-(Aminomethyl)benzyl)phosphonic Acid Dimethyl Ester Oxalate; Benzylphosphonic acid, 3-(aminomethyl)-, dimethyl ester, oxalate; Dimethyl [3-(aminomethyl)benzyl]phosphonate oxalate; Aminomethylbenzylphosphonate dimethyl ester oxalate
EINECS	Contact for details

Quality Control

Every batch of Dimethyl 3-(Aminomethyl)Benzylphosphonate Oxalate is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.