Description

6-Iodo-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is a high-value, halogenated tetrahydroisoquinoline derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research, particularly in the development of novel pharmacologically active molecules targeting the central nervous system. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and other transformations to introduce the iodo-substituted tetrahydroisoquinoline moiety.
• Ligand and Probe Development: Useful for creating molecular probes and ligands for biological target identification and validation.
• Academic Research: Utilized in universities and research institutes for methodological development and exploring new chemical space.

Basic Information

Product Name	6-Iodo-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid
CAS No.	1383132-10-2
Molecular Formula	C10H10INO2
Molecular Weight	303.10 g/mol
Synonyms	6-Iodo-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 6-Iodo-THIQ-3-COOH; 3-Carboxy-6-iodo-1,2,3,4-tetrahydroisoquinoline; 6-Iodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 1383132-10-2; 6-Iodo-3-isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-; 1,2,3,4-Tetrahydro-6-iodo-3-isoquinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Iodo-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.