Description

5-Chloroisoquinoline-3-Carboxylic Acid is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, including kinase inhibitors and other biologically active heterocycles.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical space.
• Agrochemical Development: Serves as a precursor in the creation of new active ingredients for crop protection products.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for various high-value applications.
• Ligand and Catalyst Preparation: Useful for constructing novel chelating ligands or organocatalysts due to its functionalized isoquinoline core.
• Academic Research: A valuable reagent for methodological development and exploratory synthesis in university and institutional laboratories.

Basic Information

Product Name	5-Chloroisoquinoline-3-Carboxylic Acid
CAS No.	1381949-77-4
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	5-Chloro-3-isoquinolinecarboxylic acid; 5-Chloroisoquinoline-3-carboxylic acid; 3-Carboxy-5-chloroisoquinoline; 5-Chloro-isoquinoline-3-carboxylic acid; 1381949-77-4; 5-Chloro-3-isoquinoline carboxylic acid; 5-Chloro-3-quinolinecarboxylic acid (related); 5-Chloroisoquinolin-3-yl carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Chloroisoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.