Description

4-Bromo-5,7-Difluoro-1H-Indole is a high-purity, multi-halogenated indole derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents at specific positions, makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including kinase inhibitors and other biologically relevant heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in the synthesis of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used as a building block for creating new herbicides, fungicides, and insecticides with enhanced activity and selectivity.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its halogenated indole core.
• Chemical Biology Probes: Serves as a precursor for fluorescent tags and molecular probes used in biochemical and cellular imaging studies.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories worldwide.

Basic Information

Product Name	4-Bromo-5,7-Difluoro-1H-Indole
CAS No.	1381878-59-6
Molecular Formula	C8H4BrF2N
Molecular Weight	232.03 g/mol
Synonyms	4-Bromo-5,7-difluoroindole; 5,7-Difluoro-4-bromo-1H-indole; 1H-Indole, 4-bromo-5,7-difluoro-; 4-Bromo-5,7-difluoro-1H-indole; 1381878-59-6; 4-Br-5,7-F2-indole
EINECS	Contact for details

Quality Control

Our 4-Bromo-5,7-Difluoro-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. For custom synthesis or specific purity grades (e.g., >98%, >99%), please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.