Description

1-(3-Chloroisoquinolin-6-Yl)Ethanone is a high-purity, specialized organic building block with the CAS registry number 1381812-94-7. This compound is valued for its role as a key synthetic intermediate in advanced pharmaceutical research and fine chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the isoquinoline scaffold's bioactivity.
• Material Science: Serves as a building block for creating advanced organic electronic materials and functional polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Academic & Institutional R&D: Used in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	1-(3-Chloroisoquinolin-6-Yl)Ethanone
CAS No.	1381812-94-7
Molecular Formula	C11H8ClNO
Molecular Weight	205.64 g/mol
Synonyms	6-Acetyl-3-chloroisoquinoline; 3-Chloro-6-acetylisoquinoline; 1-(3-Chloro-6-isoquinolinyl)ethanone; Ethanone, 1-(3-chloro-6-isoquinolinyl)-; 1381812-94-7; 3-Chloroisoquinoline-6-yl methyl ketone; 3-Chloro-6-isoquinolinyl methyl ketone
EINECS	Contact for details

Quality Control

Every batch of 1-(3-Chloroisoquinolin-6-Yl)Ethanone is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.