Description

2-(4-Hydroxy-2-Oxoindolin-3-Yl)Acetonitrile is a high-purity, advanced pharmaceutical intermediate with a distinct oxindole-acetonitrile structure. This compound is valued for its role as a critical building block in the synthesis of complex bioactive molecules and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• API Synthesis: Serves as a crucial building block for the development of Active Pharmaceutical Ingredients (APIs) with oxindole core structures.
• Biochemical Research: Used in medicinal chemistry research for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides and plant growth regulators.
• Fine Chemical Production: Utilized in custom synthesis and the manufacture of specialty chemicals requiring high-purity intermediates.

Basic Information

Product Name	2-(4-Hydroxy-2-Oxoindolin-3-Yl)Acetonitrile
CAS No.	1380540-77-1
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	3-(Cyanomethyl)-4-hydroxy-1,3-dihydro-2H-indol-2-one; 4-Hydroxy-3-(cyanomethyl)indolin-2-one; 2-(4-Hydroxy-2-oxo-2,3-dihydro-1H-indol-3-yl)acetonitrile; 3-(Cyanomethyl)-4-hydroxyindolin-2-one; 4-Hydroxy-3-(cyanomethyl)-2-indolinone
EINECS	Contact for details

Quality Control

Our 2-(4-Hydroxy-2-Oxoindolin-3-Yl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere such as nitrogen or argon for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.