Description

1-(5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)-2,2,2-Trichloroethanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated pyrrolopyridine core. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in the development of chemical probes to study specific biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel chemical entities.
• Academic Research: Utilized in university and institutional labs for pioneering research in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	1-(5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)-2,2,2-Trichloroethanone
CAS No.	1379670-84-4
Molecular Formula	C9H4BrCl3N2O
Molecular Weight	334.40 g/mol
Synonyms	5-Bromo-3-(trichloroacetyl)-1H-pyrrolo[2,3-b]pyridine; 2,2,2-Trichloro-1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone; 1-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-2,2,2-trichloroethan-1-one; 5-Bromo-3-trichloroacetyl-1H-pyrrolo[2,3-b]pyridine; CAS 1379670-84-4
EINECS	Contact for details

Quality Control

Our production of 1-(5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)-2,2,2-Trichloroethanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. All materials are characterized by advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.