Description

tert-Butyl (2-Chlorothiazol-5-Yl)Carbamate CAS NO 1379344-91-8 is a high-purity, advanced pharmaceutical intermediate characterized by its specific thiazole and carbamate functional groups. This compound is of significant commercial value as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug molecules, especially for antiviral, antibacterial, or kinase inhibitor therapies.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced pesticides and herbicides, leveraging the bioactivity of the chlorothiazole moiety.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring novel chemical reactions and synthesizing complex heterocyclic libraries.
• Custom Synthesis Building Block: Employed by fine chemical manufacturers for contract synthesis and the production of tailored, high-value specialty chemicals for clients.

Basic Information

Product Name	tert-Butyl (2-Chlorothiazol-5-Yl)Carbamate
CAS No.	1379344-91-8
Molecular Formula	C8H11ClN2O2S
Molecular Weight	234.70 g/mol
Synonyms	tert-Butyl N-(2-chloro-1,3-thiazol-5-yl)carbamate; 5-[[(tert-Butoxy)carbonyl]amino]-2-chlorothiazole; 2-Chloro-5-[(tert-butoxycarbonyl)amino]thiazole; Boc-2-Chloro-5-aminothiazole; (2-Chlorothiazol-5-yl)carbamic acid tert-butyl ester; tert-Butyl (2-chloro-1,3-thiazol-5-yl)carbamate; 2-Chloro-5-aminothiazole Boc derivative
EINECS	Contact for details

Quality Control

Our production of tert-Butyl (2-Chlorothiazol-5-Yl)Carbamate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming the product meets the agreed specifications. Our quality system is designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.