Description

5-(2-Bromothien-3-Yl)-3-Methyl-1,2,4-Oxadiazole is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional materials. The precise bromine and oxadiazole functionalities offer unique reactivity for cross-coupling and cyclization reactions.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the bromothiophene-oxadiazole core can contribute to novel modes of action.
• Material Science: Acts as a building block for organic electronic materials, such as semiconductors or light-emitting components for OLEDs, due to its conjugated system.
• Chemical Biology Probe Development: Employed in creating molecular probes and tags for studying biological processes and target engagement.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form more complex biaryl structures.
• Ligand Synthesis: Can be utilized in the preparation of novel ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	5-(2-Bromothien-3-Yl)-3-Methyl-1,2,4-Oxadiazole
CAS No.	1379344-42-9
Molecular Formula	C7H5BrN2OS
Molecular Weight	245.10 g/mol
Synonyms	3-Methyl-5-(2-bromothiophen-3-yl)-1,2,4-oxadiazole; 5-(2-Bromo-3-thienyl)-3-methyl-1,2,4-oxadiazole; 1,2,4-Oxadiazole, 5-(2-bromo-3-thienyl)-3-methyl-; 2-Bromo-3-(3-methyl-1,2,4-oxadiazol-5-yl)thiophene; 5-(2-Bromothiophen-3-yl)-3-methyl-1,2,4-oxadiazole
EINECS	Contact for details

Quality Control

Our 5-(2-Bromothien-3-Yl)-3-Methyl-1,2,4-Oxadiazole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.