Description

1-Chloro-5-Iodoisoquinoline is a high-value halogenated isoquinoline derivative, a crucial building block in advanced organic synthesis. Its unique bifunctional halogen pattern makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and catalyst development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its halogenated structure for bioactive molecule design.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination, enabling rapid diversification.
• Ligand Synthesis: Utilized for constructing complex nitrogen-containing ligands used in catalysis and coordination chemistry.
• Chemical Biology: Employed as a molecular probe or tag in bioconjugation and target identification studies.

Basic Information

Product Name	1-Chloro-5-Iodoisoquinoline
CAS No.	1379322-93-6
Molecular Formula	C9H5ClIN
Molecular Weight	289.50 g/mol
Synonyms	5-Iodo-1-chloroisoquinoline; Isoquinoline, 1-chloro-5-iodo-; 1-Chloro-5-iodo-isoquinoline; 1379322-93-6; 5-Iodo-1-chloro-isoquinoline; 1-Chloro-5-iodoisoquinoline; 1-Chloro-5-iodo-isoquinoline; 5-Iodo-1-chloroisoquinoline
EINECS	Contact for details

Quality Control

Our 1-Chloro-5-Iodoisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.