Description

(1R,5S)-3,8-Diazabicyclo[3.2.1]Octane is a high-purity, chiral bicyclic diamine building block of significant interest in advanced organic synthesis. This compound matters as a key scaffold for constructing complex molecules with precise three-dimensional control, which is critical for developing active pharmaceutical ingredients (APIs) and functional materials. Pharmaceutical researchers and fine chemical manufacturers need it for applications in asymmetric catalysis and as a precursor to novel drug candidates, particularly in neurological and oncological therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in central nervous system (CNS) and oncology drug discovery.
• Asymmetric Catalyst Ligand: Serves as a precursor for sophisticated chiral ligands used in transition metal catalysis to achieve high enantioselectivity in chemical transformations.
• Agrochemical Synthesis: Used in the research and development of advanced, enantiomerically pure pesticides and herbicides.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional organic materials.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for the bespoke production of complex target molecules.

Basic Information

Product Name	(1R,5S)-3,8-Diazabicyclo[3.2.1]Octane
CAS No.	1378838-39-1
Molecular Formula	C6H12N2
Molecular Weight	112.17 g/mol
Synonyms	(1R,5S)-3,8-Diazabicyclo[3.2.1]octane; (1R,5S)-3,8-Diazabicyclo[3.2.1]octane; endo-3,8-Diazabicyclo[3.2.1]octane; (1R,5S)-3,8-Diazabicyclo[3.2.1]octane; 3,8-Diazabicyclo[3.2.1]octane, (1R,5S)-; Bicyclo[3.2.1]octane, 3,8-diaza-, (1R,5S)-; (1R,5S)-3,8-Diaza-bicyclo[3.2.1]octane
EINECS	Contact for details

Quality Control

Our (1R,5S)-3,8-Diazabicyclo[3.2.1]Octane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity compliant with research and development standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.