Description

Methyl 2-Chloro-5-Methylthiazole-4-Carboxylate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound matters as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate and scale new products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the thiazole core imparts specific biological activity.
• Material Science Research: Serves as a building block for creating functionalized heterocyclic compounds used in organic electronics, ligands for catalysis, and advanced polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and other tools for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Methyl 2-Chloro-5-Methylthiazole-4-Carboxylate
CAS No.	1378819-18-1
Molecular Formula	C7H8ClNO2S
Molecular Weight	205.66 g/mol
Synonyms	Methyl 2-chloro-5-methyl-1,3-thiazole-4-carboxylate; 2-Chloro-5-methylthiazole-4-carboxylic acid methyl ester; 4-Carbomethoxy-2-chloro-5-methylthiazole; Methyl (2-chloro-5-methyl-4-thiazolyl)carboxylate; 2-Chloro-5-methyl-4-thiazolecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-5-Methylthiazole-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. Certificates of Analysis (COA) with full analytical data are provided for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.