Description

(4-Bromo-1H-Benzoimidazol-2-Yl)-Acetonitrile is a high-value brominated benzimidazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both a bromine substituent and a reactive nitrile group, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and antiviral agents targeting benzimidazole-based pharmacophores.
• Agrochemical Research: Used in developing novel fungicides and herbicides where the benzimidazole core provides bioactive properties.
• Material Science: Building block for creating specialized ligands, coordination complexes, and organic electronic materials.
• Chemical Synthesis: Serves as a versatile substrate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization via the nitrile group.
• Biochemical Tool Compound: Utilized in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Item	Details
Product Name	(4-Bromo-1H-Benzoimidazol-2-Yl)-Acetonitrile
CAS No.	1378260-17-3
Molecular Formula	C9H6BrN3
Molecular Weight	236.07 g/mol
Synonyms	4-Bromo-1H-benzimidazole-2-acetonitrile; 2-(4-Bromo-1H-benzimidazol-2-yl)acetonitrile; (4-Bromo-1H-benzo[d]imidazol-2-yl)acetonitrile; 4-Bromo-2-(cyanomethyl)-1H-benzimidazole; 1H-Benzimidazole-2-acetonitrile, 4-bromo-; 1378260-17-3; 4-Bromo-1H-benzoimidazole-2-acetonitrile
EINECS	Contact for details

Quality Control

Our (4-Bromo-1H-Benzoimidazol-2-Yl)-Acetonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.