Description

2-Chloro-1-(5-Methylthiazol-2-Yl)Ethanone is a specialized organic building block featuring a reactive α-chloroketone moiety adjacent to a methylthiazole heterocycle. This compound is of significant value in pharmaceutical and agrochemical research as a key intermediate for constructing complex molecules, particularly those containing thiazole pharmacophores. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for synthesizing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and fungicides where the thiazole ring is a key structural component.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for creating libraries of heterocyclic compounds for screening and discovery.
• Material Science Precursor: Potential use in the synthesis of specialized ligands, polymers, or functional materials with specific electronic or binding properties.

Basic Information

Product Name	2-Chloro-1-(5-Methylthiazol-2-Yl)Ethanone
CAS No.	1375710-69-2
Molecular Formula	C6H6ClNOS
Molecular Weight	175.63 g/mol
Synonyms	2-Chloro-1-(5-methyl-1,3-thiazol-2-yl)ethanone; 2-Chloro-1-(5-methylthiazol-2-yl)ethan-1-one; 1-(5-Methyl-2-thiazolyl)-2-chloroethanone; 2-Acetyl-5-methylthiazole, 2-chloro derivative; α-Chloro-5-methyl-2-acetylthiazole; 2-Chloro-1-(5-methyl-2-thienyl)ethanone (common misnomer check); 1375710-69-2
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-1-(5-Methylthiazol-2-Yl)Ethanone is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced intermediates, ensuring traceability and compliance for regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. Due to the reactive chloro-ketone group, prolonged exposure to moisture or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.