Description

Isoquinoline, 6-Bromo-1,2,3,4-Tetrahydro-8-Methyl- is a high-purity, synthetically valuable brominated tetrahydroisoquinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and insecticides with specific biological activity.
• Ligand and Catalyst Development: Used to create novel nitrogen-containing ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate in the synthesis of organic semiconductors, dyes, and photoactive materials.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Custom Synthesis: Serves as a starting point for contract manufacturing organizations (CMOs) to produce bespoke compounds for client projects.

Basic Information

Product Name	Isoquinoline, 6-Bromo-1,2,3,4-Tetrahydro-8-Methyl-
CAS No.	1375302-92-3
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	6-Bromo-8-methyl-1,2,3,4-tetrahydroisoquinoline; 8-Methyl-6-bromo-1,2,3,4-tetrahydroisoquinoline; 6-Bromo-8-methyl-3,4-dihydro-1H-isoquinoline; 1,2,3,4-Tetrahydro-6-bromo-8-methylisoquinoline; 6-Bromo-8-methyl-THIQ; Br-8-Me-THIQ
EINECS	Contact for details

Quality Control

Our Isoquinoline, 6-Bromo-1,2,3,4-Tetrahydro-8-Methyl- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization including HPLC, GC, NMR, and mass spectrometry to confirm identity and purity. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.