Description

5-Bromo-1-T-Butyl-6,7-Difluorobenzimidazole is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated benzimidazole core structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapies. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for creating compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted small-molecule therapeutics.
• Agrochemical Research: Used in the development of new fungicides and herbicides, leveraging its halogenated heterocyclic structure for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials and specialty polymers due to its stable, functionalized aromatic system.
• Chemical Synthesis: Acts as a versatile reagent in organic chemistry for constructing complex heterocyclic frameworks in academic and industrial R&D.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Bromo-1-T-Butyl-6,7-Difluorobenzimidazole
CAS No.	1375069-11-6
Molecular Formula	C11H11BrF2N2
Molecular Weight	289.12 g/mol
Synonyms	5-Bromo-1-tert-butyl-6,7-difluoro-1H-benzimidazole; 1-(tert-Butyl)-5-bromo-6,7-difluoro-1H-benzimidazole; 5-Bromo-1-(1,1-dimethylethyl)-6,7-difluoro-1H-benzimidazole; 1375069-11-6; 5-Bromo-1-t-butyl-6,7-difluorobenzimidazole; 6,7-Difluoro-5-bromo-1-tert-butylbenzimidazole
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-T-Butyl-6,7-Difluorobenzimidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure the container is kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.