Description

2-Bromo-6-Fluoro-3-Methylbenzyl Alcohol is a versatile and high-purity fluorinated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily targeted at research and development laboratories and production facilities in the pharmaceutical, agrochemical, and material science sectors, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the bromo and fluoro substituents enhance biological activity and stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination for carbon-carbon and carbon-heteroatom bond formation.
• Functional Group Transformation: The benzyl alcohol group can be readily oxidized to the corresponding aldehyde or esterified, providing a handle for further chemical diversification.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Bromo-6-Fluoro-3-Methylbenzyl Alcohol
CAS No.	1375069-06-9
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	(2-Bromo-6-fluoro-3-methylphenyl)methanol; 1-(2-Bromo-6-fluoro-3-methylphenyl)methanol; 2-Bromo-6-fluoro-3-methylbenzenemethanol; α-Hydroxymethyl-2-bromo-6-fluoro-3-methylbenzene; 2-Bromo-6-fluoro-m-tolylmethanol; 3-(Hydroxymethyl)-2-bromo-6-fluorotoluene
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluoro-3-Methylbenzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.