Description

Ethyl 6-Methoxy-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylate is a high-purity, synthetically valuable heterocyclic building block. This compound is a critical intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting neurological and cardiovascular pathways. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tetrahydroisoquinoline-based drug candidates, including potential analgesics, anti-hypertensives, and neuroprotective agents.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the construction of complex molecular libraries.
• Research & Development: Essential for academic and industrial R&D labs exploring novel heterocyclic compounds for biological activity.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals requiring a defined chiral or structural motif.

Basic Information

Product Name	Ethyl 6-Methoxy-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylate
CAS No.	1375066-30-0
Molecular Formula	C₁₃H₁₇NO₃
Molecular Weight	235.28 g/mol
Synonyms	4-Carbethoxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline; Ethyl 6-methoxy-3,4-dihydro-1H-isoquinoline-4-carboxylate; 6-Methoxy-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid ethyl ester; 4-(Ethoxycarbonyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline; 6-Methoxy-4-ethoxycarbonyl-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6-methoxyisoquinoline-4-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Methoxy-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.