Description

Methyl 2-(5-Bromothiazol-2-Yl)Acetate is a high-value brominated thiazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a functionalized scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, where its specific bromine and ester functionalities enable precise molecular modifications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that leverage the thiazole moiety for bioactivity.
• Material Science Research: Serves as a precursor for functionalized heterocyclic compounds used in organic electronic materials and ligands for catalysis.
• Chemical Biology Probes: Utilized in the creation of tagged molecules for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A requested intermediate for bespoke chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	Methyl 2-(5-Bromothiazol-2-Yl)Acetate
CAS No.	1375065-91-0
Molecular Formula	C6H6BrNO2S
Molecular Weight	236.09 g/mol
Synonyms	Methyl (5-bromo-1,3-thiazol-2-yl)acetate; 2-(5-Bromothiazol-2-yl)acetic acid methyl ester; Acetic acid, 2-(5-bromo-2-thiazolyl)-, methyl ester; Methyl 5-bromothiazole-2-acetate; 5-Bromo-2-thiazoleacetic acid methyl ester; Methyl α-(5-bromothiazol-2-yl)acetate; 1375065-91-0
EINECS	Contact for details

Quality Control

Our Methyl 2-(5-Bromothiazol-2-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.