Description

2-(5-Bromothiazol-2-Yl)Acetonitrile is a high-value brominated thiazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a reactive nitrile group adjacent to a functionalized heterocyclic scaffold, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Material Science: Serves as a precursor for functionalized polymers, liquid crystals, or organic electronic materials due to its conjugated system and reactive sites.
• Chemical Synthesis: Versatile synthon for heterocyclic chemistry, enabling further transformations such as cyclizations, cross-coupling reactions, and nucleophilic substitutions.
• Bioconjugation & Probe Development: The reactive nitrile group can be utilized for click chemistry or further functionalization to create biochemical probes and diagnostic agents.

Basic Information

Product Name	2-(5-Bromothiazol-2-Yl)Acetonitrile
CAS No.	1375064-90-6
Molecular Formula	C5H3BrN2S
Molecular Weight	203.06 g/mol
Synonyms	2-(5-Bromo-1,3-thiazol-2-yl)acetonitrile; (5-Bromothiazol-2-yl)acetonitrile; Acetonitrile, 2-(5-bromo-2-thiazolyl)-; 2-(5-Bromothiazol-2-yl)ethanenitrile; 5-Bromo-2-thiazoleacetonitrile; 2-Thiazoleacetonitrile, 5-bromo-; 1375064-90-6
EINECS	Contact for details

Quality Control

Our 2-(5-Bromothiazol-2-Yl)Acetonitrile is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.