Description

1-Acetyl-3-Bromo-5-Fluoroindole is a high-purity, multi-functional halogenated indole derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile, pre-functionalized scaffold that enables efficient synthesis of complex molecules, saving significant R&D time and resources. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in oncology and CNS (Central Nervous System) therapeutic areas.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and pesticides due to its bioactive indole core and halogen substituents.
• Material Science Precursor: Serves as a monomer or functional unit in the creation of specialized polymers and organic electronic materials.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis services targeting complex, fluorinated, and brominated heterocycles.

Basic Information

Product Name	1-Acetyl-3-Bromo-5-Fluoroindole
CAS No.	1375064-67-7
Molecular Formula	C10H7BrFNO
Molecular Weight	256.07 g/mol
Synonyms	3-Bromo-5-fluoro-1H-indol-1-yl ethanone; 3-Bromo-5-fluoro-1-acetylindole; 1-(3-Bromo-5-fluoro-1H-indol-1-yl)ethanone; 5-Fluoro-3-bromo-1-acetylindole; 1-Acetyl-5-fluoro-3-bromoindole; Ethanone, 1-(3-bromo-5-fluoro-1H-indol-1-yl)-; 3-Bromo-5-fluoroindole-1-acetate
EINECS	Contact for details

Quality Control

Our production of 1-Acetyl-3-Bromo-5-Fluoroindole adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; store away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.