Description

Ethyl 3-Bromo-6-Fluoroindole-1-Carboxylate is a high-purity, multi-functional indole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated and fluorinated structure, which enables precise molecular modifications in complex chemical pathways. It is primarily sought after by research institutions and pharmaceutical development teams for the creation of novel active pharmaceutical ingredients (APIs) and agrochemical intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop new herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Acts as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex substituents.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	Ethyl 3-Bromo-6-Fluoroindole-1-Carboxylate
CAS No.	1375064-61-1
Molecular Formula	C11H9BrFNO2
Molecular Weight	286.10 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 3-bromo-6-fluoro-, ethyl ester; Ethyl 3-bromo-6-fluoro-1H-indole-1-carboxylate; 3-Bromo-6-fluoroindole-1-carboxylic acid ethyl ester; 1375064-61-1; 3-Bromo-6-fluoro-1-indolecarboxylic acid ethyl ester; Ethyl 3-bromo-6-fluoroindole-1-carboxylate; 1-Carbethoxy-3-bromo-6-fluoroindole
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-6-Fluoroindole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.