Description

Ethyl 3-Bromo-4-Chloroindole-1-Carboxylate is a high-value, multi-halogenated indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its precise halogen substitution pattern makes it an indispensable building block for constructing complex molecular architectures with targeted biological activity. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting various therapeutic areas, including oncology and CNS disorders.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by incorporating the halogenated indole scaffold.
• Material Science: Building block for creating specialized organic electronic materials and photoactive compounds.
• Chemical Biology: Serves as a probe or linker in the development of biochemical tools and diagnostic agents.
• Academic & R&D: Fundamental reagent for methodological studies in heterocyclic and cross-coupling chemistry.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	Ethyl 3-Bromo-4-Chloroindole-1-Carboxylate
CAS No.	1375064-58-6
Molecular Formula	C11H9BrClNO2
Molecular Weight	302.55 g/mol
Synonyms	Ethyl 3-bromo-4-chloro-1H-indole-1-carboxylate; 1H-Indole-1-carboxylic acid, 3-bromo-4-chloro-, ethyl ester; 3-Bromo-4-chloroindole-1-carboxylic acid ethyl ester; 4-Chloro-3-bromoindole-1-carboxylic acid ethyl ester; Ethyl 4-chloro-3-bromo-1H-indole-1-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-4-Chloroindole-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and GC-MS for solvent residue analysis, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.