Description

Ethyl 3-Bromo-5-Fluoroindole-1-Carboxylate is a high-purity, multi-functional indole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated and fluorinated indole scaffold, which enables precise molecular modifications in complex chemical pathways. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the bioactivity of the halogenated indole core.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocyclic compound synthesis.
• Chemical Library Synthesis: Employed in combinatorial chemistry and high-throughput screening to build diverse compound libraries for biological evaluation.

Basic Information

Product Name	Ethyl 3-Bromo-5-Fluoroindole-1-Carboxylate
CAS No.	1375064-48-4
Molecular Formula	C11H9BrFNO2
Molecular Weight	286.10 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 3-bromo-5-fluoro-, ethyl ester; Ethyl 3-bromo-5-fluoro-1H-indole-1-carboxylate; 3-Bromo-5-fluoroindole-1-carboxylic acid ethyl ester; 1-Carbethoxy-3-bromo-5-fluoroindole; 3-Bromo-5-fluoro-1-ethoxycarbonylindole; Ethyl 3-bromo-5-fluoroindole-1-carboxylate; 1375064-48-4
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-Bromo-5-Fluoroindole-1-Carboxylate is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.