Description

4-Amino-Bicyclo[2.2.1]Heptane-1-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable bicyclic amino acid derivative. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is essential for research and development in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients with specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including protease inhibitors, neurological agents, and other biologically active molecules.
• Agrochemical Research: Used in developing advanced pesticides and herbicides where the rigid bicyclic structure confers specific biological activity and stability.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in catalytic asymmetric reactions to induce high enantioselectivity.
• Peptidomimetics & Conformationally Restricted Peptides: The bicyclo[2.2.1]heptane (norbornane) scaffold is used to design peptide analogs with enhanced metabolic stability and receptor selectivity.
• Material Science Research: Potential monomer or precursor for specialty polymers with unique thermal and mechanical properties.
• Academic & R&D Laboratories: Serves as a valuable reference standard and starting material for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	4-Amino-Bicyclo[2.2.1]Heptane-1-Carboxylic Acid Ethyl Ester
CAS No.	1375000-41-1
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	Ethyl 4-Aminobicyclo[2.2.1]heptane-1-carboxylate; 1-Carbethoxy-4-aminonorbornane; 4-Aminonorbornane-1-carboxylic Acid Ethyl Ester; 1-Norbornanecarboxylic acid, 4-amino-, ethyl ester; Bicyclo[2.2.1]heptane-1-carboxylic acid, 4-amino-, ethyl ester; 4-Amino-1-norbornanecarboxylic Acid Ethyl Ester; Ethyl 4-Amino-2-norbornanecarboxylate
EINECS	Contact for details

Quality Control

Our 4-Amino-Bicyclo[2.2.1]Heptane-1-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/GC), chiral purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.