Description

4-Chloro-2-(trifluoromethyl)thieno[2,3-d]pyrimidine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a fused thienopyrimidine ring system substituted with chloro and trifluoromethyl groups, makes it a critical intermediate for developing novel active compounds. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. It enables the efficient construction of complex molecules targeting a range of biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of potential drug candidates, particularly for kinase inhibitors, antiviral agents, and anticancer therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the thienopyrimidine core.
• Material Science Precursor: Acts as a building block for creating specialized organic electronic materials or ligands for catalytic systems.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	4-Chloro-2-(trifluoromethyl)thieno[2,3-d]pyrimidine
CAS No.	1374831-02-3
Molecular Formula	C7H2ClF3N2S
Molecular Weight	238.62 g/mol
Synonyms	4-Chloro-2-(trifluoromethyl)thieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidine, 4-chloro-2-(trifluoromethyl)-; 4-Chloro-2-trifluoromethylthieno[2,3-d]pyrimidine; 2-(Trifluoromethyl)-4-chlorothieno[2,3-d]pyrimidine; 4-Chloro-2-(trifluoromethyl)-thieno[2,3-d]pyrimidine; CAS 1374831-02-3
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-(trifluoromethyl)thieno[2,3-d]pyrimidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.