Description

8-(Aminomethyl)-2-Methylisoquinolin-1(2H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique isoquinolinone scaffold with an aminomethyl functional group. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical, biotechnology, and fine chemical companies engaged in the development of new therapeutic agents, particularly in areas targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting kinase inhibition or receptor modulation.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of molecular probes to study enzyme function and cellular signaling pathways.
• Fine Chemical Synthesis: Serves as a specialized building block for the preparation of complex heterocyclic compounds in custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	8-(Aminomethyl)-2-Methylisoquinolin-1(2H)-One
CAS No.	1374652-33-1
Molecular Formula	C11H12N2O
Molecular Weight	188.23 g/mol
Synonyms	1(2H)-Isoquinolinone, 8-(aminomethyl)-2-methyl-; 2-Methyl-8-(aminomethyl)isoquinolin-1(2H)-one; 8-(Aminomethyl)-2-methyl-1,2-dihydroisoquinolin-1-one; 8-(Aminomethyl)-2-methyl-1H-isoquinolin-1-one; 1374652-33-1; 2-Methyl-8-(aminomethyl)-1(2H)-isoquinolinone
EINECS	Contact for details

Quality Control

Our 8-(Aminomethyl)-2-Methylisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.