Description

5-(Aminomethyl)-2-Methylisoquinolin-1(2H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique isoquinolinone scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of small-molecule therapeutics, particularly for central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for active pharmaceutical ingredients (APIs) in drug discovery and development pipelines.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• CNS Drug Development: A valuable scaffold for synthesizing compounds targeting neurological receptors and enzymes.
• Oncology Research: Employed in the synthesis of potential kinase inhibitors and other anti-cancer agents.
• Chemical Biology: Utilized as a probe or linker in the development of chemical tools for biological target identification.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke organic synthesis.

Basic Information

Product Name	5-(Aminomethyl)-2-Methylisoquinolin-1(2H)-One
CAS No.	1374652-19-3
Molecular Formula	C11H12N2O
Molecular Weight	188.23 g/mol
Synonyms	5-(Aminomethyl)-2-methyl-1,2-dihydroisoquinolin-1-one; 2-Methyl-5-(aminomethyl)isoquinolin-1(2H)-one; 1(2H)-Isoquinolinone, 5-(aminomethyl)-2-methyl-; 5-(Aminomethyl)-2-methyl-1,2-dihydroisoquinolin-1-one; 1374652-19-3; 5-Aminomethyl-2-methylisoquinolin-1-one
EINECS	Contact for details

Quality Control

Our 5-(Aminomethyl)-2-Methylisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.