Description

8-(Aminomethyl)Isoquinolin-1(2H)-One is a high-purity, functionalized isoquinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its versatile aminomethyl handle, which enables facile derivatization and incorporation into complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and by fine chemical manufacturers producing specialized intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with novel modes of action.
• Ligand Synthesis: Used to create chelating agents and ligands for catalysis and metal complexation studies.
• Fluorescent Probe Development: Serves as a core structure for synthesizing advanced fluorescent dyes and molecular probes used in bioimaging and diagnostics.
• Material Science: Intermediate in the production of specialty polymers and organic electronic materials.
• Academic & Contract Research: Essential reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	8-(Aminomethyl)Isoquinolin-1(2H)-One
CAS No.	1374651-98-5
Molecular Formula	C₁₀H₁₀N₂O
Molecular Weight	174.20 g/mol
Synonyms	1(2H)-Isoquinolinone, 8-(aminomethyl)-; 8-(Aminomethyl)-1,2-dihydroisoquinolin-1-one; 8-(Aminomethyl)-1,2-dihydroisoquinolin-1-one; 8-(Aminomethyl)isoquinolin-1-ol; 8-Aminomethyl-1,2-dihydroisoquinolin-1-one; 1,2-Dihydro-8-(aminomethyl)isoquinolin-1-one; 8-(Aminomethyl)-1(2H)-isoquinolinone
EINECS	Contact for details

Quality Control

Our 8-(Aminomethyl)Isoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.