Description

tert-Butyl 5-Bromo-4-Methoxy-1H-Indazole-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and pesticides with specific biological activity.
• Chemical Synthesis: Serves as a versatile building block for constructing complex indazole-based heterocycles in academic and industrial R&D.
• Material Science: Potential monomer or precursor for the development of specialty polymers and advanced organic materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	tert-Butyl 5-Bromo-4-Methoxy-1H-Indazole-1-Carboxylate
CAS No.	1374651-94-1
Molecular Formula	C₁₃H₁₅BrN₂O₃
Molecular Weight	327.17 g/mol
Synonyms	1-Boc-5-bromo-4-methoxy-1H-indazole; 5-Bromo-4-methoxy-1H-indazole-1-carboxylic acid tert-butyl ester; tert-Butyl 5-bromo-4-methoxyindazole-1-carboxylate; 1H-Indazole-1-carboxylic acid, 5-bromo-4-methoxy-, 1,1-dimethylethyl ester; 1374651-94-1; Boc-5-bromo-4-methoxyindazole
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Bromo-4-Methoxy-1H-Indazole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.