Description

6-Bromo-5-Isopropoxy-1H-Indazole is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated indazole structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of targeted small-molecule drugs.
• Kinase Inhibitor Development: Used in research and production of protein kinase inhibitors for cancer treatment.
• Agrochemical Research: Acts as a scaffold for developing new active ingredients in crop protection products.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Industrial R&D: Used in exploratory chemistry to discover new compounds with potential pharmacological activity.

Basic Information

Product Name	6-Bromo-5-Isopropoxy-1H-Indazole
CAS No.	1374651-77-0
Molecular Formula	C10H11BrN2O
Molecular Weight	255.11 g/mol
Synonyms	6-Bromo-5-isopropoxy-1H-indazole; 5-Isopropoxy-6-bromo-1H-indazole; 1H-Indazole, 6-bromo-5-(1-methylethoxy)-; 6-Bromo-5-(propan-2-yloxy)-1H-indazole; 1374651-77-0; 6-Br-5-iPrO-1H-Indazole
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Isopropoxy-1H-Indazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The material may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.