Description

1-Chloroisoquinolin-7-Amine is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique chlorinated isoquinoline scaffold enables the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a precursor for creating organic ligands in catalysis and for synthesizing advanced organic electronic materials.
• Chemical Biology: Employed as a molecular probe or tag in biochemical research due to its reactive amine and chloro functional groups.
• Academic & Contract Research: Essential for methodological development and novel synthetic route exploration in university and CRO laboratories.

Basic Information

Product Name	1-Chloroisoquinolin-7-Amine
CAS No.	1374651-74-7
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	7-Amino-1-chloroisoquinoline; 1-Chloro-7-isoquinolinamine; 1-Chloro-7-aminoisoquinoline; 1-Chloro-7-isoquinolylamine; 1-Chloroisoquinolin-7-ylamine; 1374651-74-7; 7-Amino-1-chloro-isoquinoline
EINECS	Contact for details

Quality Control

Our 1-Chloroisoquinolin-7-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to meet the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.