Description

1-Chloroisoquinolin-8-Ol is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique chlorinated isoquinoline scaffold enables the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders and cancers.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its bioactive heterocyclic core.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials or host materials in OLED device fabrication.
• Ligand Synthesis: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Material Science: Incorporated into polymers and advanced materials to impart specific electronic or photophysical properties.

Basic Information

Item	Detail
Product Name	1-Chloroisoquinolin-8-Ol
CAS No.	1374651-67-8
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	8-Hydroxy-1-chloroisoquinoline; 1-Chloro-8-hydroxyisoquinoline; 1-Chloro-8-isoquinolinol; 1-Chloroisoquinolin-8-ol; Isoquinolin-8-ol, 1-chloro-; 1374651-67-8
EINECS	Contact for details

Quality Control

Our 1-Chloroisoquinolin-8-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable performance in your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.