Description

6-(Aminomethyl)-2-Methylisoquinolin-1(2H)-One is a high-purity, advanced pharmaceutical intermediate featuring a functionalized isoquinolinone core. This compound matters for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate this privileged scaffold into new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its reactive aminomethyl group.
• Agrochemical Development: Used in the research and synthesis of novel pesticides and herbicides that leverage the isoquinolinone pharmacophore.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Biochemical Probe Development: Utilized in academic and industrial research to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	6-(Aminomethyl)-2-Methylisoquinolin-1(2H)-One
CAS No.	1374651-55-4
Molecular Formula	C11H12N2O
Molecular Weight	188.23 g/mol
Synonyms	6-(Aminomethyl)-2-methyl-1,2-dihydroisoquinolin-1-one; 2-Methyl-6-(aminomethyl)isoquinolin-1(2H)-one; 1(2H)-Isoquinolinone, 6-(aminomethyl)-2-methyl-; 6-(Aminomethyl)-2-methyl-1,2-dihydroisoquinolin-1-one; 1374651-55-4; 6-Aminomethyl-2-methylisoquinolin-1-one
EINECS	Contact for details

Quality Control

Our 6-(Aminomethyl)-2-Methylisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.