Description

6-(Aminomethyl)Isoquinolin-1(2H)-One is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique fused-ring structure containing both an isoquinoline core and a reactive aminomethyl functional group, enabling its use in constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and scaffold-hopping strategies to explore new chemical space and improve pharmacokinetic properties.
• Agrochemical Development: Serves as a precursor in the creation of new herbicides, fungicides, or insecticides with novel modes of action.
• Chemical Biology Probes: Utilized in the development of molecular probes and tools for studying enzyme function and biological pathways.
• Ligand Synthesis: The aminomethyl group facilitates its incorporation into complex ligands for catalysis or metal-organic frameworks (MOFs).
• Advanced Material Precursor: Potential use in the synthesis of organic semiconductors or fluorescent dyes due to the conjugated isoquinoline system.

Basic Information

Product Name	6-(Aminomethyl)Isoquinolin-1(2H)-One
CAS No.	1374651-53-2
Molecular Formula	C₁₀H₁₀N₂O
Molecular Weight	174.20 g/mol
Synonyms	1(2H)-Isoquinolinone, 6-(aminomethyl)-; 6-(Aminomethyl)-1,2-dihydroisoquinolin-1-one; 6-(Aminomethyl)-1H-isoquinolin-1-one; 6-(Aminomethyl)isoquinolin-1-ol (tautomer); 6-(Aminomethyl)-2H-isoquinolin-1-one; 1-Isoquinolinol, 6-(aminomethyl)-, 2H-Tautomer; 6-Aminomethyl-1-hydroxyisoquinoline
EINECS	Contact for details

Quality Control

Our 6-(Aminomethyl)Isoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.