Description

7-(Aminomethyl)-2-Methylisoquinolin-1(2H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique isoquinolinone scaffold. This compound matters for its critical role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. Pharmaceutical, agrochemical, and fine chemical manufacturers need this material for creating novel drug candidates and specialty chemicals, where its functional groups enable precise molecular modifications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential therapeutic agents targeting neurological disorders, inflammation, and oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Employed in the development of novel pesticides and herbicides, leveraging its heterocyclic structure.
• Fine Chemical Production: Acts as a building block for synthesizing specialty dyes, pigments, and functional materials.
• Bioconjugation & Probe Development: The aminomethyl group facilitates conjugation reactions for creating biochemical probes and diagnostic agents.
• Academic & Contract Research: Utilized in university and CRO laboratories for exploratory synthetic chemistry and method development.

Basic Information

Product Name	7-(Aminomethyl)-2-Methylisoquinolin-1(2H)-One
CAS No.	1374651-48-5
Molecular Formula	C11H12N2O
Molecular Weight	188.23 g/mol
Synonyms	2-Methyl-7-(aminomethyl)isoquinolin-1(2H)-one; 1(2H)-Isoquinolinone, 7-(aminomethyl)-2-methyl-; 7-(Aminomethyl)-2-methyl-1,2-dihydroisoquinolin-1-one; 2-Methyl-7-(aminomethyl)-1,2-dihydroisoquinolin-1-one; 2-Methyl-1-oxo-1,2-dihydroisoquinoline-7-methanamine
EINECS	Contact for details

Quality Control

Our 7-(Aminomethyl)-2-Methylisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.