Description

6-Bromo-5-Fluoroisatin is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique halogenated isatin core makes it a critical intermediate for developing novel pharmaceutical compounds and agrochemicals. This compound is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the synthesis of kinase inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used as a building block for developing new active ingredients with herbicidal or pesticidal properties.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialized polymers and dyes.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Academic & Contract Research: Fundamental reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	6-Bromo-5-Fluoroisatin
CAS No.	1374208-41-9
Molecular Formula	C8H3BrFNO2
Molecular Weight	244.02 g/mol
Synonyms	5-Fluoro-6-bromoisatin; 6-Bromo-5-fluoro-1H-indole-2,3-dione; 1H-Indole-2,3-dione, 6-bromo-5-fluoro-; 5-Fluoro-6-bromo-2,3-dihydroxyindole; 6-Bromo-5-fluorooxindole (tautomer); 5-Fluoro-6-bromoisatinic acid (deprotonated form)
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Fluoroisatin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.