Description

Boronic Acid, B-[3-Bromo-5-(1,1-Dimethylethyl)Phenyl]- is a high-purity, synthetically valuable organoboron building block, identified by CAS NO 1373881-94-7. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures in modern organic synthesis. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex biaryl motifs common in many drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where specific bromo-substituted phenylboronic acids are required for structure-activity optimization.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular architecture is crucial.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other transition metal-catalyzed processes.
• Chemical Biology & Probe Synthesis: Utilized in the design and construction of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Item	Details
Product Name	Boronic Acid, B-[3-Bromo-5-(1,1-Dimethylethyl)Phenyl]-
CAS No.	1373881-94-7
Molecular Formula	C12H16BBrO2
Molecular Weight	283.97 g/mol
Synonyms	(3-Bromo-5-tert-butylphenyl)boronic acid; 3-Bromo-5-tert-butylbenzeneboronic acid; B-(3-Bromo-5-tert-butylphenyl)boronic acid; 3-Bromo-5-(tert-butyl)phenylboronic acid; 3-Bromo-5-(1,1-dimethylethyl)benzeneboronic acid; 3-Bromo-5-tert-butylphenylboronic acid; Boronic acid, B-[3-bromo-5-(1,1-dimethylethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-[3-Bromo-5-(1,1-Dimethylethyl)Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.