Description

5-Methoxycarbonyl-1H-Indole-2-Boronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of complex molecule assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing indole-based scaffolds found in active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Critical building block for synthesizing novel indole-containing drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators with indole motifs.
• Material Science Research: Serves as a precursor for creating functionalized organic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation reagents for studying biological systems.
• Academic & Contract Research: A vital reagent for methodology development and complex molecule synthesis in academic and industrial R&D laboratories.
• Custom Synthesis & Scale-Up: Supplied for custom synthesis projects requiring reliable, high-purity boronic acid components for pilot and commercial-scale production.

Basic Information

Product Name	5-Methoxycarbonyl-1H-Indole-2-Boronic Acid
CAS No.	1373870-41-7
Molecular Formula	C10H10BNO4
Molecular Weight	219.01 g/mol
Synonyms	Methyl 2-Borono-1H-indole-5-carboxylate; 1H-Indole-5-carboxylic acid, 2-borono-, methyl ester; 5-(Methoxycarbonyl)-1H-indole-2-boronic acid; 2-Borono-5-methoxycarbonylindole; Methyl 5-indolecarboxylate-2-boronic acid; 5-Carbomethoxyindole-2-boronic acid; 5-Methoxycarbonylindol-2-ylboronic acid
EINECS	Contact for details

Quality Control

Our 5-Methoxycarbonyl-1H-Indole-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.