Description

(5-Bromo-4-Ethylpyridin-3-Yl)Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions, which are fundamental to pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists working in pharmaceutical discovery, agrochemical development, and the synthesis of functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active compound libraries.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the development of organic electronic materials, such as OLED emitters and charge-transport molecules, due to its functionalized pyridine core.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and activity-based protein profiling (ABPP) reagents.
• Catalyst Ligand Synthesis: Serves as a starting material for creating novel bidentate and tridentate ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs producing bespoke organic compounds for client projects.

Basic Information

Product Name	(5-Bromo-4-Ethylpyridin-3-Yl)Boronic Acid
CAS No.	1373522-78-1
Molecular Formula	C7H9BBrNO2
Molecular Weight	229.87 g/mol
Synonyms	5-Bromo-4-ethyl-3-pyridineboronic acid; 3-Borono-5-bromo-4-ethylpyridine; (5-Bromo-4-ethyl-3-pyridinyl)boronic acid; B-(5-Bromo-4-ethyl-3-pyridinyl)boronic acid; 4-Ethyl-5-bromopyridine-3-boronic acid; 1373522-78-1; 5-Bromo-4-ethylpyridine-3-boronic acid
EINECS	Contact for details

Quality Control

Every batch of (5-Bromo-4-Ethylpyridin-3-Yl)Boronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (HPLC/NMR), identity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and reactivity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.