Description

7-Chloro-5-Fluoro-1H-Indazole is a high-purity fluorinated indazole derivative, serving as a critical building block in modern organic synthesis. Its value lies in its unique halogenated structure, which is essential for modulating the biological activity and physicochemical properties of advanced molecules. This intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and anticancer agent discovery.
• Agrochemical Synthesis: Used in creating advanced herbicides and pesticides where the indazole core contributes to biological efficacy.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential precursor for the synthesis of specialty polymers, ligands, or organic electronic materials due to its fused heterocyclic structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	7-Chloro-5-Fluoro-1H-Indazole
CAS No.	1373223-64-3
Molecular Formula	C7H4ClFN2
Molecular Weight	170.57 g/mol
Synonyms	7-Chloro-5-fluoro-1H-indazole; 5-Fluoro-7-chloro-1H-indazole; 1H-Indazole, 7-chloro-5-fluoro-; 1373223-64-3; 7-Chloro-5-fluoroindazole; 5-Fluoro-7-chloroindazole; 7-Chloro-5-fluoro-1H-benzo[d]imidazole (common misnomer)
EINECS	Contact for details

Quality Control

Our 7-Chloro-5-Fluoro-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.