Description

n-Ethylsuccinimide-D5 is a deuterated analog of n-ethylsuccinimide, where five hydrogen atoms are replaced with deuterium, a stable isotope of hydrogen. This deuteration makes it an invaluable internal standard and reference material for precise quantitative analysis using mass spectrometry and NMR spectroscopy. It is primarily required by analytical laboratories and research institutions in the pharmaceutical, agrochemical, and environmental testing sectors for method development, validation, and ensuring regulatory compliance in trace-level analysis.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis in pharmacokinetic and bioanalytical studies.
• Deuterated Reference Material for quantitative NMR (qNMR) to determine the purity of analytical standards.
• Metabolite Tracing and stable isotope labeling studies in pharmaceutical and biochemical research.
• Method Development and Validation for regulatory testing in pharmaceutical quality control laboratories.
• Impurity Profiling and characterization of related substances in active pharmaceutical ingredients (APIs).
• Environmental Analysis as a labeled standard for detecting and quantifying chemical residues.

Basic Information

Product Name	n-Ethylsuccinimide-D5
CAS No.	1370698-98-8
Molecular Formula	C6D5H4NO2
Molecular Weight	130.16 g/mol (deuterated form)
Synonyms	1-Ethyl-2,5-pyrrolidinedione-D5; N-Ethylsuccinimide-d5; Ethylsuccinimide-D5; Deuterated N-Ethylsuccinimide; 1-Ethylpyrrolidine-2,5-dione-d5; Succinimide, N-ethyl-, D5; Perdeuterated N-ethylsuccinimide (5-D)
EINECS	Contact for details

Quality Control

Our n-Ethylsuccinimide-D5 is manufactured under strict quality management systems to ensure high isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR and Mass Spectrometry to confirm deuteration level and chemical purity. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications for isotopic enrichment, chemical purity, and identity, supporting its use in GLP and ISO 17025 accredited laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled to minimize prolonged exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.