Description

6-Acetamido-4-(Trifluoromethyl)Pyridin-3-Ylboronic Acid is a high-value boronic acid derivative and a crucial building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and herbicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Material Science: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: An essential reagent in academic and industrial R&D for the efficient formation of carbon-carbon bonds to create complex heterocyclic scaffolds.
• Bioconjugation: Potential use in the development of bioconjugates and probes for diagnostic applications, utilizing the boronic acid moiety for selective binding.

Basic Information

Product Name	6-Acetamido-4-(Trifluoromethyl)Pyridin-3-Ylboronic Acid
CAS No.	1370351-47-5
Molecular Formula	C8H8BF3N2O3
Molecular Weight	248.0 g/mol
Synonyms	6-Acetamido-4-(trifluoromethyl)-3-pyridineboronic acid; 3-Borono-6-acetamido-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-6-acetamidopyridin-3-ylboronic acid; 6-Acetylamino-4-(trifluoromethyl)pyridine-3-boronic acid; (6-Acetamido-4-(trifluoromethyl)pyridin-3-yl)boronic acid; 3-Pyridineboronic acid, 6-(acetylamino)-4-(trifluoromethyl)-; B-[6-Acetamido-4-(trifluoromethyl)-3-pyridinyl]boronic acid
EINECS	Contact for details

Quality Control

Our 6-Acetamido-4-(Trifluoromethyl)Pyridin-3-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and reactivity. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.