Description

(1R,5S,6R)-Rel-8-Azabicyclo[3.2.1]Octan-6-Ol CAS NO 1369774-29-7 is a high-purity, stereochemically defined bicyclic amino alcohol building block. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecular architectures with precise three-dimensional control. It is primarily sought after by pharmaceutical and agrochemical research organizations for the development of new active ingredients, where its rigid scaffold serves as a key chiral intermediate.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its structural motif can contribute to biological activity and selectivity.
• Catalyst Ligand Precursor: Serves as a starting material for the synthesis of sophisticated chiral ligands used in asymmetric catalysis, enabling more efficient and selective chemical transformations.
• Chemical Biology Probe Development: Employed in the construction of molecular probes and tools for studying biological systems and enzyme mechanisms.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic routes to complex natural products.
• Fine Chemical Production: Integrated into multi-step syntheses for the manufacture of high-value, specialty chemicals requiring specific stereochemical configurations.

Basic Information

Item	Details
Product Name	(1R,5S,6R)-Rel-8-Azabicyclo[3.2.1]Octan-6-Ol
CAS No.	1369774-29-7
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	(1R,5S,6R)-8-Azabicyclo[3.2.1]octan-6-ol; rel-(1R,5S,6R)-8-Azabicyclo[3.2.1]octan-6-ol; 8-Azabicyclo[3.2.1]octan-6-ol, (1R,5S,6R)-rel-; 8-Azabicyclo[3.2.1]octan-6-ol endo-; endo-8-Azabicyclo[3.2.1]octan-6-ol; Tropan-6-ol; 6-Hydroxy-8-azabicyclo[3.2.1]octane
EINECS	Contact for details

Quality Control

Our (1R,5S,6R)-Rel-8-Azabicyclo[3.2.1]Octan-6-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.