Description

2-Bromo-4H,5H,6H-Cyclopenta[B]Thiophen-4-One is a high-value brominated heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and scalable route development.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as organic semiconductors and conductive polymers.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized to develop molecular probes for studying biological pathways and protein functions.
• Academic & Contract Research: A valuable reagent for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2-Bromo-4H,5H,6H-Cyclopenta[B]Thiophen-4-One
CAS No.	1369353-77-4
Molecular Formula	C7H5BrOS
Molecular Weight	217.08 g/mol
Synonyms	2-Bromocyclopenta[b]thiophen-4(5H)-one; 2-Bromo-4,5-dihydro-6H-cyclopenta[b]thiophen-4-one; 2-Bromo-4-oxo-4,5,6,7-tetrahydrocyclopenta[b]thiophene; 4H-Cyclopenta[b]thiophen-4-one, 2-bromo-4,5,6,7-tetrahydro-; 2-Bromo-4,5,6,7-tetrahydro-4H-cyclopenta[b]thiophen-4-one
EINECS	Contact for details

Quality Control

Our 2-Bromo-4H,5H,6H-Cyclopenta[B]Thiophen-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.